Liquid Amnion Cryopreserved

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  • Published literature documents that amniotic fluid may contain important growth factors, extracellular matrix molecules, hyaluronic acid, fibronectin, laminin, prostaglandins, and cells*
  • Published benefits of amniotic fluid may include reduced inflammation, reduced fibrosis/scarring, decreased pain, and anti-adhesion properties*
  • The fluid may be used independently or in combination with autologous tissue or other forms of allograft tissue
  • Aseptically processed and tested per USP <71> sterility tests
  • Packaged with a shelf life of 1 year which must be stored at -70•C or colder
  • Manufactured at an AATB facility
  • Cleared for market by FDA
  • Available in vials ranging from 0.5ml to 2.0ml in volume
  • Click here to download instructions


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Amnios™ is a cryopreserved allograft derived from human amninioticotic fluid.

Amniotic fluid is a versatile, powerful tissue which supports the development of the fetus in utero.  The properties of amniotic fluid which benefit the fetus also make it an effective material for covering wounds, while at the same time contributing to an envir0nment conducive to the regeneration of healthy tissue.

Allogenic human birth tissue, including amniotic fluid, have an established record of use in a variety of surgical and clinical settings. Published literature suggests that amniotic fluid may contain important growth factors, extracellular matrix molecules, hyaluronic acid, fibronectin, laminin, prostaglandins, and cells.

Benefits of amniotic fluid may include:

  • A safe, natural covering for wounds
  • Inhibiting influence of inflammation
  • Reduced fibrosis, scarring, and adhesion at the surgical site

Intended for topical application as a covering over wounds or areas of localized inflammation.

Birth tissue are recovered during planned Cesarean sections and processed aseptically in a manner to preserve the graft’s inherent properties.

Tissue Safety

  • Placental donors go through a rigorous pre-screening qualification and are tested according to FDA guidelines for infectious disease.
  • Collection of the donor tissue is performed during planned Cesarean section delivery by appropriately licensed personnel.
  • Processed in accordance with the standards and guidelines established by the American Association of Tissue Banks (AATB)

Handling & Storage Guidelines

  • Store at -70C or colder.  Thaw only prior to use
  • Allow product to thaw by standing at room temperature and apply directly to the injury, would, or are of inflammation
  • See instructions for use for a more detailed description.

1.    Nyman E, Huss F, Nyman T, Junker J, Kratz G. (2013 Apr) Hyaluronic acid, an important factor in the wound healing properties of amniotic fluid: in vitro studies of re-epithelization in human skin wounds. J Plast Surg Hand Surg. 47(2):89-92
2.    Adzick NS, Lorenz HP. (1994 Jul) Cells, matrix, growth factors, and the surgeon. The biology of scarless fetal wound repair. Annals of Surgery.;220(1):10-18
3.    Gao X, Devoe LD, Given KS. (1994 Aug) Effects of amniotic fluid on proteases: a possible role of amniotic fluid in fetal wound healing. Annals of Plastic Surgery. 33(2):128-134; discussion 134-135.
4.    Bolat E, Kocamaz E, Kulahcilar Z, Yilmaz A, Topcu A, Ozdemir M, Coskun ME. (2013 Dec) Investigation of efficacy of mitomycin-C, sodium hyaluronate and human amniotic fluid in preventing epidural fibrosis and adhesion using a rat laminectomy model. Asian Spine J. 7(4):253-9.
5.    Cobanglu U, Kutlu N, Karacal N, Kosucu P. (2005 Dec) Effect of human amniotic fluid on bone healing. J Surg Res. 129(2):283-7
6.    Ozgenel GY, Filiz G, Ozcan M. (2004 Jul) Effects of human amniotic fluid on cartilage regeneration from free perchondrial grafts in rabbits. Br J Plast Surg. 57(5):423-8.
7.    Rosner M, Hipany K, Shanmugasundaram B, Lubec G, Hengstschlager M (2012 Jun) Amniotic Fluid Stem Cells: Future Perspectives. Stem Cells Int. 2012:741810

Additional information


0.50cc, 1.00cc, 1.25cc, 2.00cc


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